Cellg8

Clinically-Validated
Nutrient Delivery

CELLg8® Liposomes safely deliver nutrients through the digestive system and into the body, significantly improving the absorption and bioavailability of key nutrients. The structure, size, and efficiency of the liposomes are validated using industry leading test methods, and their benefits are backed by 5 clinical studies ensuring efficacy.

Functional Benefits

Bioavailability

Absorption

Side Effects

Stability

Taste + Smell

Validated Liposomes

Liposomes have been used as biological delivery structures for decades. The concept is simple: use the same material that encases our bodies’ cells to deliver nutrients to it. Liposomes, like our cell membranes, are made of a phospholipid bilayer, allowing them to move into the body with ease and even deposit their contents directly into cells.

Liposome

Structure of a Liposome

TEM Imaging of Cellg8 Liposomes

CELLg8 Liposomes are fully validated and characterized using industry-leading technologies.

TEM imaging is completed to ensure proper liposome shape and structure. Dynamic Light Scattering provides data on particle size distribution. CELLg8's proprietary process results in an average encapsulation rate of 92%.

Value-Added Benefits

In addition to the improved bioavailability and absorption of nutrients, CELLg8 Liposomes provide technical and formulation benefits which add value. CELLg8 Liposomes improve the stability of many nutrients, reducing the overage amounts required. They effectively mask unwanted flavors and smells. And they are able to reduce or eliminate unwanted side effects associated with some nutrients.

Clinical Research

Ultimately, the most important aspect of any nutritional ingredient is how it works in the body and what benefits it will bring to customers. Multiple CELLg8 Liposomes have clinical research showing not just their ability to deliver nutrients, but also to provide health benefits to consumers. With available claims on multiple nutrients, CELLg8 Liposomes provide the necessities for new product development.

Vitamin C

When taking 4g of regular Vitamin C versus 4g of Liposomal Vitamin C, the liposomal form delivered higher levels of Vitamin C to the bloodstream. This led to a reduction in oxidative stress, even during stressful situations. The new version of Liposomal Vitamin C (CELLg8®) has a small particle size with 92% of the particles being tightly controlled in size, showing the consistent quality of the product.

Green Tea (EGCG)

EGCG is a type of plant compound called a catechin. Catechins are part of a larger group of compounds called polyphenols. EGCG and other catechins protect cells from damage caused by harmful particles called free radicals. Eating foods high in catechins can help reduce damage from free radicals.

Glutathione

A study was done to see if a special liposomal form of glutathione, which is found in CELLg8® glutathione, could increase levels of glutathione in the blood and help with detoxification. Seven people took a regular glutathione powder, then after a week's break took the CELLg8® liposomal glutathione liquid. The results showed that the liposomal form increased blood levels of glutathione by 22%, while the regular powder did not change levels. In another study, four people took 750 mg of CELLg8® glutathione twice a day for 30 days. This led to improved liver function and detoxification as shown by a decrease in bilirubin and a 39% decrease in mercury.

Iron

A study was done with 25 healthy people who took either a multivitamin/mineral supplement in a special form called liposomal or a regular multivitamin/mineral supplement. Their blood was tested for iron and magnesium levels at the start and every two hours for six hours. The results showed that iron levels were higher in people who took the liposomal supplement compared to the regular one. However, magnesium levels were not different between the two groups. The researchers found that the special liposomal form helped the body absorb iron better.

Vitamin B12

A study was done with six people to compare the effects of two different forms of vitamin B12 - a liquid form and a capsule form. Each person was given 3 mg of vitamin B12 in one form, waited 14 days, and then took the other form. Almost all the people had higher levels of vitamin B12 in their blood after taking the capsule form compared to the liquid form. The average increase was six times more after taking the capsule form.

Multivitamin

This study investigated the impact of ingesting a liposomal multivitamin and mineral (MVM) supplement compared to a non-liposomal MVM supplement on the appearance and clearance of vitamins and minerals in the bloodstream. In a double-blind, randomized, and counterbalanced trial, 34 healthy individuals fasted for 12 hours and consumed either the non-liposomal (NL) or liposomal (L) MVM supplement along with a standardized snack. Blood samples were taken at 0, 2, 4, and 6 hours after ingestion and analyzed for a range of vitamins and minerals. Statistical analyses revealed significant interactions between treatment and time for the evaluated vitamins and minerals, indicating differential effects between the two supplements. Various parameters such as volume distribution, median residence time, clearance rates, elimination half-life, and distribution/absorption phase were also affected differently by the two treatments for different vitamins and minerals. Specifically, liposomal MVM ingestion resulted in lower volume distribution of vitamins compared to non-liposomal MVM sources, suggesting improved clearance and absorption despite similar nutrient intake. These findings demonstrate that coating an MVM supplement with liposomes alters the pharmacokinetic profiles of individual nutrients. Liposomal formulations have proven to be significantly more effective with the same dosage.

The ingestion of a liposomal multivitamin and mineral (MVM) supplement has distinct effects on the concentrations of certain vitamins and minerals in the bloodstream, their distribution throughout the body, clearance rates, and removal from the blood when compared to a non-liposomal MVM supplement. These findings are significant because they are the first to show that encapsulating an MVM supplement with liposomes can influence the pharmacokinetic (PK) profile of multiple vitamins and minerals present in the supplement, thereby impacting the availability of nutrients. Further research could establish this as a more efficient method of delivering vitamins and minerals in dietary supplements. However, more studies are necessary to determine how coating an MVM supplement with liposomes affects tissue absorption, metabolic function, and overall health. The current findings support the notion that enveloping an MVM supplement with liposomes influences the bioavailability of individual nutrients contained within the supplement.